Arecoline-induced myofibroblast transdifferentiation from human buccal mucosal fibroblasts is mediated by ZEB1

Oral submucous fibrosis (OSF) is considered as a pre-cancerous condition of the oral mucosa and is highly associated with habitual areca quid chewing. Arecoline is the major alkaloid in areca quid and is thought to be involved in the pathogenesis of OSF. Our previous studies have demonstrated that a...

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Hlavní autoři: Chang, Yu-Chao, Tsai, Chung-Hung, Lai, You-Liang, Yu, Cheng-Chia, Chi, Wan-Yu, Li, Jung Jung, Chang, Wen-Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons Ltd 2014
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000120/
https://ncbi.nlm.nih.gov/pubmed/24400868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12219
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