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Elevation of S100A4 Expression in Buccal Mucosal Fibroblasts by Arecoline: Involvement in the Pathogenesis of Oral Submucous Fibrosis

BACKGROUND: S100A4, a member of the calcium-binding proteins, is dramatically elevated in a variety of fibrotic diseases. Areca quid chewing is the most important etiological factor in the pathogenesis of oral submucous fibrosis (OSF). OSF has been considered as a pre-cancerous condition of oral muc...

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Detalhes bibliográficos
Main Authors: Yu, Cheng-Chia, Tsai, Chung-Hung, Hsu, Hsin-I, Chang, Yu-Chao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561403/
https://ncbi.nlm.nih.gov/pubmed/23383075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055122
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