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Antibody-modified T cells: CARs take the front seat for hematologic malignancies

T cells redirected to specific antigen targets with engineered chimeric antigen receptors (CARs) are emerging as powerful therapies in hematologic malignancies. Various CAR designs, manufacturing processes, and study populations, among other variables, have been tested and reported in over 10 clinic...

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Detalhes bibliográficos
Main Authors: Maus, Marcela V., Grupp, Stephan A., Porter, David L., June, Carl H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999751/
https://ncbi.nlm.nih.gov/pubmed/24578504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-11-492231
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