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Antibody-modified T cells: CARs take the front seat for hematologic malignancies

T cells redirected to specific antigen targets with engineered chimeric antigen receptors (CARs) are emerging as powerful therapies in hematologic malignancies. Various CAR designs, manufacturing processes, and study populations, among other variables, have been tested and reported in over 10 clinic...

詳細記述

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書誌詳細
主要な著者: Maus, Marcela V., Grupp, Stephan A., Porter, David L., June, Carl H.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999751/
https://ncbi.nlm.nih.gov/pubmed/24578504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-11-492231
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