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Antibody-modified T cells: CARs take the front seat for hematologic malignancies

T cells redirected to specific antigen targets with engineered chimeric antigen receptors (CARs) are emerging as powerful therapies in hematologic malignancies. Various CAR designs, manufacturing processes, and study populations, among other variables, have been tested and reported in over 10 clinic...

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Dades bibliogràfiques
Autors principals: Maus, Marcela V., Grupp, Stephan A., Porter, David L., June, Carl H.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999751/
https://ncbi.nlm.nih.gov/pubmed/24578504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-11-492231
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