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Regional distribution of synaptic markers and APP correlate with distinct clinicopathological features in sporadic and familial Alzheimer’s disease

Recent studies suggest that subcortical structures, including striatum, are vulnerable to amyloid-β accumulation and other neuropathological features in familial Alzheimer’s disease due to autosomal dominant mutations. We explored differences between familial and sporadic Alzheimer’s disease that mi...

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Hlavní autoři: Shinohara, Mitsuru, Fujioka, Shinsuke, Murray, Melissa E., Wojtas, Aleksandra, Baker, Matthew, Rovelet-Lecrux, Anne, Rademakers, Rosa, Das, Pritam, Parisi, Joseph E., Graff-Radford, Neill R., Petersen, Ronald C., Dickson, Dennis W., Bu, Guojun
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999719/
https://ncbi.nlm.nih.gov/pubmed/24625695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awu046
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