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Automated Objective Determination of Percentage of Malignant Nuclei for Mutation Testing

Detection of DNA mutations in tumor tissue can be a critical companion diagnostic test prior to prescription of a targeted therapy. Each method for detection of these mutations is associated with an analytic sensitivity that is a function of the percentage of tumor cells present in the specimen. Cur...

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Detalhes bibliográficos
Main Authors: Viray, Hollis, Coulter, Madeline, Li, Kevin, Lane, Kristin, Madan, Aruna, Mitchell, Kisha, Schalper, Kurt, Hoyt, Clifford, Rimm, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999345/
https://ncbi.nlm.nih.gov/pubmed/24162261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAI.0b013e318299a1f6
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