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Rapid Response to Selection, Competitive Release and Increased Transmission Potential of Artesunate-Selected Plasmodium chabaudi Malaria Parasites

The evolution of drug resistance, a key challenge for our ability to treat and control infections, depends on two processes: de-novo resistance mutations, and the selection for and spread of resistant mutants within a population. Understanding the factors influencing the rates of these two processes...

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Autors principals: Pollitt, Laura C., Huijben, Silvie, Sim, Derek G., Salathé, Rahel M., Jones, Matthew J., Read, Andrew F.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999151/
https://ncbi.nlm.nih.gov/pubmed/24763470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004019
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