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20-Hydroxyeicosatetraenoic Acid Impairs Endothelial Insulin Signaling by Inducing Phosphorylation of the Insulin Receptor Substrate-1 at Ser(616)
20-hydroxyeicosatetraenoic acid (20-HETE) induces endothelial dysfunction and is correlated with diabetes. This study was designed to investigate the effects of 20-HETE on endothelial insulin signaling.Human umbilical vein endothelial cells (HUVECs) or C57BL/6J mice were treated with 20-HETE in the...
Wedi'i Gadw mewn:
Prif Awduron: | , , , , , , |
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Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
Public Library of Science
2014
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3998975/ https://ncbi.nlm.nih.gov/pubmed/24763529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095841 |
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