Discrete Molecular Dynamics Can Predict Helical Prestructured Motifs in Disordered Proteins

Intrinsically disordered proteins (IDPs) lack a stable tertiary structure, but their short binding regions termed Pre-Structured Motifs (PreSMo) can form transient secondary structure elements in solution. Although disordered proteins are crucial in many biological processes and designing strategies...

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Bibliografske podrobnosti
Main Authors: Szöllősi, Dániel, Horváth, Tamás, Han, Kyou-Hoon, Dokholyan, Nikolay V., Tompa, Péter, Kalmár, Lajos, Hegedűs, Tamás
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998973/
https://ncbi.nlm.nih.gov/pubmed/24763499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095795
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