Cyclin B–Cdk1 inhibits protein phosphatase PP2A-B55 via a Greatwall kinase–independent mechanism

Entry into M phase is governed by cyclin B–Cdk1, which undergoes both an initial activation and subsequent autoregulatory activation. A key part of the autoregulatory activation is the cyclin B–Cdk1–dependent inhibition of the protein phosphatase 2A (PP2A)–B55, which antagonizes cyclin B–Cdk1. Great...

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Bibliographic Details
Main Authors: Okumura, Eiichi, Morita, Atsushi, Wakai, Mizuho, Mochida, Satoru, Hara, Masatoshi, Kishimoto, Takeo
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2014
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998810/
https://ncbi.nlm.nih.gov/pubmed/24616226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201307160
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