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Yoking OX40 to regulation of IL-9
The secretion of cytokines by helper T cells is affected by the cytokine environment and by costimulatory signals. Engagement of the receptor OX40 on T cells increases expression of the transcription factor TRAF6, activates the alternative transcription factor NF-κB pathway and induces the productio...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3998371/ https://ncbi.nlm.nih.gov/pubmed/22990899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2421 |
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