Dual Anti-OX40/IL-2 Therapy Augments Tumor Immunotherapy via IL-2R-Mediated Regulation of OX40 Expression

The provision of T cell co-stimulation via members of the TNFR super-family, including OX40 (CD134) and 4-1BB (CD137), provides critical signals that promote T cell survival and differentiation. Recent studies have demonstrated that ligation of OX40 can augment T cell-mediated anti-tumor immunity in...

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Detaylı Bibliyografya
Asıl Yazarlar: Redmond, William L., Triplett, Todd, Floyd, Kevin, Weinberg, Andrew D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319580/
https://ncbi.nlm.nih.gov/pubmed/22496812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034467
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