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Subclonal variant calling with multiple samples and prior knowledge

Motivation: Targeted resequencing of cancer genes in large cohorts of patients is important to understand the biological and clinical consequences of mutations. Cancers are often clonally heterogeneous, and the detection of subclonal mutations is important from a diagnostic point of view, but presen...

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Detaylı Bibliyografya
Asıl Yazarlar: Gerstung, Moritz, Papaemmanuil, Elli, Campbell, Peter J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998123/
https://ncbi.nlm.nih.gov/pubmed/24443148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt750
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