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Subclonal variant calling with multiple samples and prior knowledge

Motivation: Targeted resequencing of cancer genes in large cohorts of patients is important to understand the biological and clinical consequences of mutations. Cancers are often clonally heterogeneous, and the detection of subclonal mutations is important from a diagnostic point of view, but presen...

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書誌詳細
主要な著者: Gerstung, Moritz, Papaemmanuil, Elli, Campbell, Peter J.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998123/
https://ncbi.nlm.nih.gov/pubmed/24443148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt750
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