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Subclonal variant calling with multiple samples and prior knowledge
Motivation: Targeted resequencing of cancer genes in large cohorts of patients is important to understand the biological and clinical consequences of mutations. Cancers are often clonally heterogeneous, and the detection of subclonal mutations is important from a diagnostic point of view, but presen...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3998123/ https://ncbi.nlm.nih.gov/pubmed/24443148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt750 |
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