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Subclonal variant calling with multiple samples and prior knowledge

Motivation: Targeted resequencing of cancer genes in large cohorts of patients is important to understand the biological and clinical consequences of mutations. Cancers are often clonally heterogeneous, and the detection of subclonal mutations is important from a diagnostic point of view, but presen...

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Bibliografski detalji
Glavni autori: Gerstung, Moritz, Papaemmanuil, Elli, Campbell, Peter J.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998123/
https://ncbi.nlm.nih.gov/pubmed/24443148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt750
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