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Subclonal variant calling with multiple samples and prior knowledge

Motivation: Targeted resequencing of cancer genes in large cohorts of patients is important to understand the biological and clinical consequences of mutations. Cancers are often clonally heterogeneous, and the detection of subclonal mutations is important from a diagnostic point of view, but presen...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Gerstung, Moritz, Papaemmanuil, Elli, Campbell, Peter J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998123/
https://ncbi.nlm.nih.gov/pubmed/24443148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt750
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