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Trinucleotide repeats and long homopeptides in genes and proteins associated with nervous system disease and development.

Several human neurological disorders are associated with proteins containing abnormally long runs of glutamine residues. Strikingly, most of these proteins contain two or more additional long runs of amino acids other than glutamine. We screened the current human, mouse, Drosophila, yeast, and Esche...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Karlin, S, Burge, C
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39980/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8643671/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.4.1560
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