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Human Adipose-Derived Stromal/Stem Cells Induce Functional CD4(+)CD25(+)FoxP3(+)CD127(−) Regulatory T Cells Under Low Oxygen Culture Conditions

Human adipose tissue stromal/stem cells (ASCs) are known to induce proliferation of resting T cells under ambient (21%) O(2) conditions; however, ASCs exist physiologically under lower oxygen (5% O(2)) conditions in adipose tissue. The effects of low oxygen levels on ASC immunomodulation of T cells...

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Detalhes bibliográficos
Main Authors: Frazier, Trivia P., McLachlan, James B., Gimble, Jeffrey M., Tucker, Hugh A., Rowan, Brian G.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3997145/
https://ncbi.nlm.nih.gov/pubmed/24405386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2013.0152
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