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Human Full-Length Coagulation Factor X and a GLA Domain-Derived 40-mer Polypeptide Bind to Different Regions of the Adenovirus Serotype 5 Hexon Capsomer

The interaction of human adenovirus (HAdV)-C5 and many other adenoviruses with blood coagulation factors (e.g., human factor X, FX) involves the binding of their GLA domain to the hexon capsomers, resulting in high levels of hepatotropism and potential hepatotoxicity. In this study, we tested the po...

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Bibliografische gegevens
Hoofdauteurs: Sumarheni, Sudir, Hong, Saw See, Josserand, Véronique, Coll, Jean-Luc, Boulanger, Pierre, Schoehn, Guy, Fender, Pascal
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Mary Ann Liebert, Inc. 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3997141/
https://ncbi.nlm.nih.gov/pubmed/24512117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2013.222
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