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Topiramate Treatment of Heavy Drinkers: Moderation by a GRIK1 Polymorphism

OBJECTIVE: Topiramate has been shown to reduce drinking and heavy drinking in alcohol-dependent individuals whose goal was to stop drinking. The present study evaluated the efficacy and tolerability of topiramate in heavy drinkers whose treatment goal was to reduce drinking to safe levels. METHOD: W...

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Autores principales: Kranzler, Henry R., Covault, Jonathan, Feinn, Richard, Armeli, Stephen, Tennen, Howard, Arias, Albert J., Gelernter, Joel, Pond, Timothy, Oncken, Cheryl, Kampman, Kyle M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3997125/
https://ncbi.nlm.nih.gov/pubmed/24525690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.ajp.2013.13081014
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