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GRIK1 Genotype and Daily Expectations of Alcohol’s Positive Effects Moderate the Reduction of Heavy Drinking by Topiramate

Using retrospective reports obtained during treatment visits in 138 heavy drinkers, we found that topiramate’s reduction of heavy drinking was moderated by a polymorphism (rs2832407) in GRIK1, which encodes the GluK1 kainate subunit (Kranzler et al., 2014a). A subsequent analysis of that 12-week top...

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Detalhes bibliográficos
Publicado no:Exp Clin Psychopharmacol
Main Authors: Kranzler, Henry R., Armeli, Stephen, Tennen, Howard, Gelernter, Joel, Covault, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251491/
https://ncbi.nlm.nih.gov/pubmed/25436841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1037/a0038350
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