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GRIK1 Genotype and Daily Expectations of Alcohol’s Positive Effects Moderate the Reduction of Heavy Drinking by Topiramate

Using retrospective reports obtained during treatment visits in 138 heavy drinkers, we found that topiramate’s reduction of heavy drinking was moderated by a polymorphism (rs2832407) in GRIK1, which encodes the GluK1 kainate subunit (Kranzler et al., 2014a). A subsequent analysis of that 12-week top...

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Vydáno v:Exp Clin Psychopharmacol
Hlavní autoři: Kranzler, Henry R., Armeli, Stephen, Tennen, Howard, Gelernter, Joel, Covault, Jonathan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251491/
https://ncbi.nlm.nih.gov/pubmed/25436841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1037/a0038350
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