Thymidylate synthase polymorphisms in genomic DNA as clinical outcome predictors in a European population of advanced non-small cell lung cancer patients receiving pemetrexed

BACKGROUND: We studied whether thymidylate synthase (TS) genotype has an independent prognostic/predictive impact on a European population of advanced non-small cell lung cancer (NSCLC) patients receiving pemetrexed. METHODS: Twenty-five patients treated with pemetrexed-based regimens were included....

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Dettagli Bibliografici
Autori principali: Arévalo, Estefanía, Castañón, Eduardo, López, Inés, Salgado, Josefa, Collado, Víctor, Santisteban, Marta, Rodríguez-Ruiz, María, Martín, Patricia, Zubiri, Leire, Patiño-García, Ana, Rolfo, Christian, Gil-Bazo, Ignacio
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996904/
https://ncbi.nlm.nih.gov/pubmed/24726028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-98
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