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Thymidylate Synthase Expression Determines Pemetrexed Targets and Resistance Development in Tumour Cells

Although treatment options for cancer patients are increasing every year, the drug resistance problem remains very present. It is very difficult to find a drug that acts equally on tumours of the same histology as the individual's genetic characteristics often determine the response to treatmen...

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Main Authors: Buqué, Aitziber, Aresti, Unai, Calvo, Begoña, Sh. Muhialdin, Jangi, Muñoz, Alberto, Carrera, Sergio, Azkona, Eider, Rubio, Itziar, López-Vivanco, Guillermo
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652812/
https://ncbi.nlm.nih.gov/pubmed/23675481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063338
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