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Cytotoxicity of Cyclometalated Platinum Complexes Based on Tridentate NCN and CNN-coordinating ligands: Remarkable Coordination Dependence

A series of cyclometalated platinum complexes with diverse coordination patterns and geometries were screened for their anticancer activity. It was discovered that the NʌCʌN-coordinated platinum complex based on 1,3-di(pyridyl)benzene displayed much higher cytotoxicity against human lung cancer cell...

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Detalhes bibliográficos
Main Authors: Vezzu, Dileep A. k., Lu, Qun, Chen, Yan-Hua, Huo, Shouquan
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996840/
https://ncbi.nlm.nih.gov/pubmed/24531534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2014.01.021
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