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A highly efficient cocaine detoxifying enzyme obtained by computational design
Compared to naturally occurring enzymes, computationally designed enzymes are usually much less efficient, with their catalytic activities being more than six orders of magnitude below the diffusion limit. Here we use a two-step computational design approach, combined with experimental work, to desi...
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| Main Authors: | , , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3996704/ https://ncbi.nlm.nih.gov/pubmed/24643289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4457 |
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