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In Vivo Regulation of NGF-Mediated Functions by Nedd4-2 Ubiquitination of TrkA

Trk neurotrophin receptor ubiquitination in response to ligand activation regulates signaling, trafficking, and degradation of the receptors. However, the in vivo consequences of Trk ubiquitination remain to be addressed. We have developed a mouse model with a mutation in the TrkA neurotrophin recep...

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Detalhes bibliográficos
Main Authors: Yu, Tao, Calvo, Laura, Anta, Begoña, López-Benito, Saray, López-Bellido, Roger, Vicente-García, Cristina, Tessarollo, Lino, Rodriguez, Raquel E., Arévalo, Juan C.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996226/
https://ncbi.nlm.nih.gov/pubmed/24760869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4271-13.2014
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