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In Vivo Regulation of NGF-Mediated Functions by Nedd4-2 Ubiquitination of TrkA
Trk neurotrophin receptor ubiquitination in response to ligand activation regulates signaling, trafficking, and degradation of the receptors. However, the in vivo consequences of Trk ubiquitination remain to be addressed. We have developed a mouse model with a mutation in the TrkA neurotrophin recep...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Society for Neuroscience
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3996226/ https://ncbi.nlm.nih.gov/pubmed/24760869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4271-13.2014 |
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