Cysteine Sulfinic Acid Decarboxylase Regulation: A Role for FXR and SHP in Murine Hepatic Taurine Metabolism

BACKGROUND: Bile acid synthesis is regulated by nuclear receptors including farnesoid X receptor (FXR) and small heterodimer partner (SHP), and by fibroblast growth factor15/19 (FGF15/19). Because bile acid synthesis involves amino acid conjugation, we hypothesized that hepatic cysteine sulfinic aci...

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Hlavní autoři: Kerr, Thomas A., Matsumoto, Yuri, Matsumoto, Hitoshi, Xie, Yan, Hirschberger, Lawrence L., Stipanuk, Martha H., Anakk, Sayeepriyadarshini, Moore, David D., Watanabe, Mitsuhiro, Kennedy, Susan, Davidson, Nicholas O.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995905/
https://ncbi.nlm.nih.gov/pubmed/24033844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/hepr.12230
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