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DNA METHYLATION PROFILES IN TYPE 1 DIABETES TWINS POINT TO STRONG EPIGENETIC EFFECTS ON ETIOLOGY
Type 1 diabetes (T1D) shows ~ 40% concordance rate in monozygotic twins (MZ) suggesting a role for environmental factors and/or epigenetic modifications in the etiology of the disease. The aim of our study was to dissect the contribution of epigenetic factors, particularly, DNA methylation (DNAm), t...
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| Main Authors: | , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3995844/ https://ncbi.nlm.nih.gov/pubmed/24210274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2013.10.001 |
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