DNA METHYLATION PROFILES IN TYPE 1 DIABETES TWINS POINT TO STRONG EPIGENETIC EFFECTS ON ETIOLOGY

Type 1 diabetes (T1D) shows ~ 40% concordance rate in monozygotic twins (MZ) suggesting a role for environmental factors and/or epigenetic modifications in the etiology of the disease. The aim of our study was to dissect the contribution of epigenetic factors, particularly, DNA methylation (DNAm), t...

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Detalhes bibliográficos
Main Authors: Stefan, Mihaela, Zhang, Weijia, Conception, Erlinda, Yi, Zhengzi, Tomer, Yaron
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995844/
https://ncbi.nlm.nih.gov/pubmed/24210274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2013.10.001
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