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Advanced glycation end products potentiate citrated plasma-evoked oxidative and inflammatory reactions in endothelial cells by up-regulating protease-activated receptor-1 expression

Advanced glycation end products (AGEs) and receptor RAGE interaction contribute to endothelial cell damage in diabetes. Several thrombogenic abnormalities are also involved in diabetic vascular complications. However, the pathological role of thrombin and protease-activated receptor-1 (PAR-1) system...

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Detalhes bibliográficos
Main Authors: Ishibashi, Yuji, Matsui, Takanori, Ueda, Seiji, Fukami, Kei, Yamagishi, Sho-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995632/
https://ncbi.nlm.nih.gov/pubmed/24624928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-13-60
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