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The human lysozyme promoter directs reporter gene expression to activated myelomonocytic cells in transgenic mice.

The 5' region of the human lysozyme gene from -3500 to +25 was fused to a chloramphenicol acetyltransferase (CAT) reporter gene and three transgenic founder mice were obtained. All three transgenic lines showed the same pattern of CAT enzyme expression in adult mouse tissues that was consistent with...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Clarke, S, Greaves, D R, Chung, L P, Tree, P, Gordon, S
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39956/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8643649/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.4.1434
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