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Genes with a large intronic burden show greater evolutionary conservation on the protein level
BACKGROUND: The existence of introns in eukaryotic genes is believed to provide an evolutionary advantage by increasing protein diversity through exon shuffling and alternative splicing. However, this eukaryotic feature is associated with the necessity of exclusion of intronic sequences, which requi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3995522/ https://ncbi.nlm.nih.gov/pubmed/24629165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-14-50 |
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