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ROS-mediated upregulation of Noxa overcomes chemoresistance in chronic lymphocytic leukemia

In recent years considerable progress has been made in treatment strategies for chronic lymphocytic leukemia (CLL). However, the disease remains incurable because of the development of chemoresistance. Strategies to overcome resistance mechanisms are therefore highly needed. At least two mechanisms...

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Detalhes bibliográficos
Main Authors: Tonino, SH, van Laar, J, van Oers, MH, Wang, JY, Eldering, E, Kater, AP
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995409/
https://ncbi.nlm.nih.gov/pubmed/20935673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.441
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