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Site-specific functionalization of proteins and their applications to therapeutic antibodies

Protein modifications are often required to study structure and function relationships. Instead of the random labeling of lysine residues, methods have been developed to (sequence) specific label proteins. Next to chemical modifications, tools to integrate new chemical groups for bioorthogonal react...

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Detalhes bibliográficos
Main Authors: van Vught, Remko, Pieters, Roland J, Breukink, Eefjan
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology (RNCSB) Organization 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995230/
https://ncbi.nlm.nih.gov/pubmed/24757499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5936/csbj.201402001
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