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Enhanced Membrane Pore Formation through High-Affinity Targeted Antimicrobial Peptides

Many cationic antimicrobial peptides (AMPs) target the unique lipid composition of the prokaryotic cell membrane. However, the micromolar activities common for these peptides are considered weak in comparison to nisin, which follows a targeted, pore-forming mode of action. Here we show that AMPs can...

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Detalhes bibliográficos
Main Authors: Arnusch, Christopher J., Pieters, Roland J., Breukink, Eefjan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387250/
https://ncbi.nlm.nih.gov/pubmed/22768121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039768
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