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Role of Unfolded Protein Response Dysregulation in Oxidative Injury of Retinal Pigment Epithelial Cells

Aims: Age-related macular degeneration (AMD), a major cause of legal blindness in the elderly, is associated with genetic and environmental risk factors, such as cigarette smoking. Recent evidence shows that cigarette smoke (CS) that contains high levels of potent oxidants preferably targets retinal...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Chen, Cano, Marisol, Wang, Joshua J., Li, Jingming, Huang, Chuangxin, Yu, Qiang, Herbert, Terence P., Handa, James T., Zhang, Sarah X.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995121/
https://ncbi.nlm.nih.gov/pubmed/24053669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5240
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