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Foxo1 integrates insulin signaling with mitochondrial function in the liver

Type 2 diabetes is a complex disease that is marked by the dysfunction of glucose and lipid metabolism. Hepatic insulin resistance is especially pathogenic in type 2 diabetes, as it dysregulates fasting and postprandial glucose tolerance and promotes systemic dyslipidemia and nonalcoholic fatty live...

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Bibliografiska uppgifter
Huvudupphovsmän: Cheng, Zhiyong, Guo, Shaodong, Copps, Kyle, Dong, Xiaochen, Kollipara, Ramya, Rodgers, Joseph T, Depinho, Ronald A, Puigserver, Pere, White, Morris F
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994712/
https://ncbi.nlm.nih.gov/pubmed/19838201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2049
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