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Triosephosphate Isomerase Is Dispensable In Vitro yet Essential for Mycobacterium tuberculosis To Establish Infection

Triosephosphate isomerase (TPI) catalyzes the interconversion of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (G3P). This reaction is required for glycolysis and gluconeogenesis, and tpi has been predicted to be essential for growth of Mycobacterium tuberculosis. However, when st...

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書誌詳細
主要な著者: Trujillo, Carolina, Blumenthal, Antje, Marrero, Joeli, Rhee, Kyu Y., Schnappinger, Dirk, Ehrt, Sabine
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Microbiology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994511/
https://ncbi.nlm.nih.gov/pubmed/24757211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00085-14
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