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A high-performance thioredoxin-based scaffold for peptide immunogen construction: proof-of-concept testing with a human papillomavirus epitope

Escherichia coli thioredoxin has been previously exploited as a scaffold for the presentation/stabilization of peptide aptamers as well as to confer immunogenicity to peptide epitopes. Here we focused on other key features of thioredoxin that are of general interest for the production of safer and m...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Canali, Elena, Bolchi, Angelo, Spagnoli, Gloria, Seitz, Hanna, Rubio, Ivonne, Pertinhez, Thelma A., Müller, Martin, Ottonello, Simone
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994442/
https://ncbi.nlm.nih.gov/pubmed/24751665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04729
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