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The Downregulation of Somatic A-Type K(+) Channels Requires the Activation of Synaptic NMDA Receptors in Young Hippocampal Neurons of Rats

The downregulation of A-type K(+) channels (I(A) channels) accompanying enhanced somatic excitability can mediate epileptogenic conditions in mammalian central nervous system. As I(A) channels are dominantly targeted by dendritic and postsynaptic processings during synaptic plasticity, it is presuma...

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Autori principali: Kang, Moon-Seok, Yang, Yoon-Sil, Kim, Seon-Hee, Park, Joo-Min, Eun, Su-Yong, Jung, Sung-Cherl
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Korean Physiological Society and The Korean Society of Pharmacology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994300/
https://ncbi.nlm.nih.gov/pubmed/24757375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2014.18.2.135
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