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The Downregulation of Somatic A-Type K(+) Channels Requires the Activation of Synaptic NMDA Receptors in Young Hippocampal Neurons of Rats

The downregulation of A-type K(+) channels (I(A) channels) accompanying enhanced somatic excitability can mediate epileptogenic conditions in mammalian central nervous system. As I(A) channels are dominantly targeted by dendritic and postsynaptic processings during synaptic plasticity, it is presuma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kang, Moon-Seok, Yang, Yoon-Sil, Kim, Seon-Hee, Park, Joo-Min, Eun, Su-Yong, Jung, Sung-Cherl
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Korean Physiological Society and The Korean Society of Pharmacology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994300/
https://ncbi.nlm.nih.gov/pubmed/24757375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2014.18.2.135
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