Characterization of a Novel Single-Chain Bispecific Antibody for Retargeting of T Cells to Tumor Cells via the TCR Co-Receptor CD8

There is currently growing interest in retargeting of effector T cells to tumor cells via bispecific antibodies (bsAbs). Usually, bsAbs are directed on the one hand to the CD3 complex of T cells and on the other hand to a molecule expressed on the surface of the target cell. A bsAb-mediated cross-li...

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Detalhes bibliográficos
Main Authors: Michalk, Irene, Feldmann, Anja, Koristka, Stefanie, Arndt, Claudia, Cartellieri, Marc, Ehninger, Armin, Ehninger, Gerhard, Bachmann, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994066/
https://ncbi.nlm.nih.gov/pubmed/24751697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095517
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