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Formation of a Polarised Primitive Endoderm Layer in Embryoid Bodies Requires Fgfr/Erk Signalling

The primitive endoderm arises from the inner cell mass during mammalian pre-implantation development. It faces the blastocoel cavity and later gives rise to the extraembryonic parietal and visceral endoderm. Here, we investigate a key step in primitive endoderm development, the acquisition of apico-...

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Autori principali: Doughton, Gail, Wei, Jun, Tapon, Nicolas, Welham, Melanie J., Chalmers, Andrew D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994041/
https://ncbi.nlm.nih.gov/pubmed/24752320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095434
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