Development of an Adenovirus-Based Respiratory Syncytial Virus Vaccine: Preclinical Evaluation of Efficacy, Immunogenicity, and Enhanced Disease in a Cotton Rat Model

The lack of a vaccine against respiratory syncytial virus (RSV) is a challenging and serious gap in preventive medicine. Herein, we characterize the immunogenicity of an adenovirus serotype 5-based RSV vaccine encoding the fusion (F) protein (Ad5.RSV-F) and the protection provided following immuniza...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Kim, Eun, Okada, Kaori, Beeler, Judy A., Crim, Roberta L., Piedra, Pedro A., Gilbert, Brian E., Gambotto, Andrea
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2014
Aiheet:
Vaccines and Antiviral Agents
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993798/
https://ncbi.nlm.nih.gov/pubmed/24574396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03194-13
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia