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Deciphering the Role of the Gag-Pol Ribosomal Frameshift Signal in HIV-1 RNA Genome Packaging

A key step of retroviral replication is packaging of the viral RNA genome during virus assembly. Specific packaging is mediated by interactions between the viral protein Gag and elements in the viral RNA genome. In HIV-1, similar to most retroviruses, the packaging signal is located within the 5′ un...

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Autori principali: Nikolaitchik, Olga A., Hu, Wei-Shau
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993742/
https://ncbi.nlm.nih.gov/pubmed/24453371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03745-13
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