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Optimization of Standard In-House 24-Locus Variable-Number Tandem-Repeat Typing for Mycobacterium tuberculosis and Its Direct Application to Clinical Material

Variable-number tandem-repeat (VNTR) typing with a panel of 24 loci is the current gold standard in the molecular typing of Mycobacterium tuberculosis complex isolates. However, because of technical problems, a part of the loci often cannot be amplified by multiplex PCRs. Therefore, a considerable n...

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Main Authors: de Beer, Jessica L., Akkerman, Onno W., Schürch, Anita C., Mulder, Arnout, van der Werf, Tjip S., van der Zanden, Adri G. M., van Ingen, Jakko, van Soolingen, Dick
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993658/
https://ncbi.nlm.nih.gov/pubmed/24501023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.03436-13
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