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A Concise Synthesis of Carolacton

[Image: see text] A synthesis of carolacton, a myxobacterial natural product that has profound effects on Streptococcus mutans biofilms, is reported. The synthesis proceeds via a longest linear sequence of 14 steps from an Evans β-ketoimide and enabled preliminary evaluations of the effects of late-...

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Detalhes bibliográficos
Main Authors: Hallside, Michal S., Brzozowski, Richard S., Wuest, William M., Phillips, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993612/
https://ncbi.nlm.nih.gov/pubmed/24483250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol500004k
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