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ANKRD1 Acts as a Transcriptional Repressor of MMP13 via the AP-1 Site

The transcriptional cofactor ANKRD1 is sharply induced during wound repair, and its overexpression enhances healing. We recently found that global deletion of murine Ankrd1 impairs wound contraction and enhances necrosis of ischemic wounds. A quantitative PCR array of Ankrd1(−/−) (KO) fibroblasts in...

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Bibliografiske detaljer
Main Authors: Almodóvar-García, Karinna, Kwon, Minjae, Samaras, Susan E., Davidson, Jeffrey M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993579/
https://ncbi.nlm.nih.gov/pubmed/24515436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01357-13
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