Global Deletion of Ankrd1 Results in a Wound-Healing Phenotype Associated with Dermal Fibroblast Dysfunction

The expression of ankyrin repeat domain protein 1 (Ankrd1), a transcriptional cofactor and sarcomeric component, is strongly elevated by wounding and tissue injury. We developed a conditional Ankrd1(fl/fl) mouse, performed global deletion with Sox2-cre, and assessed the role of this protein in cutan...

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Bibliographic Details
Published in:Am J Pathol
Main Authors: Samaras, Susan E., Almodóvar-García, Karinna, Wu, Nanjun, Yu, Fang, Davidson, Jeffrey M.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2015
Subjects:
Regular Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278243/
https://ncbi.nlm.nih.gov/pubmed/25452119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.09.018
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